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LC-Forte/R

lc-forte

The world's first HPLC preparative device, LC-Forte/R, has been designed and developed so that MPLC columns and glass columns can also be used.

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Features

  • Preparative device designed for both high-/low- pressure chromatography Ideal for purification in the crude stage through to the final stage.
  • 3 variable-wavelengths UV detector available as a standard feature.
  • Use friendly operation provided by touch input on graphic screen.
  • Compact design but equipped with multiple functions such as recycling function, automatic programming function, etc.
  • Easy maintenance.

High purity purification utilizing recycling preparation

Ibuprofen enantiomers were purified by utilizing recycling mode of LC-Forte/R. Recycling chromatography is effective when method optimization of chiral isolation is difficult on single column separation. Recycling method offers high purity and high recovery purification. Furthermore, no solvent is consumed during recycling mode. It greatly contributes reduction of solvent consumption on purification.

Column :CHIRAL ART Cellulose-C 10 μm,
  250 X 20 mmI.D.
Flow rate :20 mL/min
Detection :UV at 265 nm
Injection :5 mL (10 mg/mL)
System :LC-Forte/R
 
Single Column
Recycling
Enantiomeric purity (%ee )
Fr.1 (R)(- -)-Ibuprofen
Fr.2 (S)(- +)-Ibuprofen

95.0 
96.8 

98.4 
99.2 
Yield (%)
84 
95 
Solvent consumption
(mL solvent/g product)
9,523 
1,276 

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Specification

Model
LC-Forte/R
LC-Forte/R100
Flow rate range (mL/min)
0.1-50.0
0.1-100
Device pressure limit (MPa)
30
30 (0.1-50 mL/min)
20 (50-90 mL/min)
Dimension (W×D×H)
660 × 500 × 430 mm
Control software
LC-Forte/R Software
Optional
Available detectors (UV+RI, RI, etc)
Fraction collector
Software for PC

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