FAQ

Feature of materials

• What are the features of YMC ODS Columns?
• How different are ODS-A, AM and AQ?
• How different are YMC-Pack Polyamine II, PA-G and NH2?
• What is “Endcapping”?
• Are there ODS columns used with 100% aqueous mobile phase?

Column handling

• What is the upper limit of column pressure?
• What are the applicable pH range and temperature?
• How should we store the columns?
• How can we evaluate the performance of columns?
• What is the shipping solvent?
• How to clean the columns?
• Do we need Guard columns?
• What is the "Connector type (W)"?
• What is required in system and flow rate for using semi-micro columns?
• How to scale-up a column for preparative isolation/purification?

Solution of column trouble

Troubue shooting tips

• What should I do when the column pressure rises up?
• What are the solutions for poor peak shapes?
• What are the solutions for ghost peaks?
• What should I do if columns are dried?
• What should I do if the column fails to provide reproducibility?
• I still have poor retention after adding ion pair reagent to mobile phase. Why?