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Meteoric Core

Meteoric Core is core-shell columns with outstanding resolution for UHPLC & HPLC. Meteoric Core can be used across a wide pH range and provides excellent peak shape for basic and coordination compounds compared to conventional columns or competitors'. This feature enables smoother method development. Meteoric Core is ideal for ultra fast and high resolution analysis. Meteoric Core can reduce its backpressure by half compared to sub-2 μm columns with the same resolution as this. Meteoric Core can be used with conventional HPLC as well as UHPLC.

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Specification

Name Meteoric Core C18 Meteoric Core C18 BIO Meteoric Core C8
Base particle Core-Shell type silica gel
Particle size ( μm) 2.7
Pore size (Å) 80 160 80
Specific surface area (m2/g) 150 90 150
Bonding Trifunctional
Carbon content (%) 7 5 5
Endcapping Yes
pH range 1.5-10 1.5-9
USP Classification L1 L1 L7



Excellent peak shape on basic compounds

Meteoric Core C18 column is a high resolution column which provides excellent peak shapes for basic compounds (Peak 1 and 2) compared to sub-2 μm Core-Shell columns. Chromatographers can expect ultrafast analysis of basic compounds with highly quantitative and sensitive analysis by using Meteoric Core C18.

Column 50 X 2.1 mmI.D.
Eluent 20 mM KH2PO4-K2HPO4 (pH 6.9)/acetonitrile (65/35)
Flow rate 0.2 mL/min
Temperature   40°C
Detection UV at 235 nm
Sample 1. Chlorpheniramine
2. Dextromethorphan
3. Propyl p-hydroxybenzoate (I.S.)

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Excellent peak shape on coordination compounds

Meteoric Core C18 is able to provide excellent peak shapes for coordination compounds which are often adsorbed to a column, resulting from a strong interaction with impurities such as trace amount of metal ion. Meteoric Core is suitable for a quantitative analysis of coordination compounds.

Column 50 X 2.1 mmI.D.
Eluent acetonitrile/0.1% phosphoric acid (40/60)
Flow rate 0.2 mL/min
Temperature   40°C
Detection UV at 254 nm

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High column efficiency

Meteoric Core C18 has high column efficiency which is almost equivalent to sub-2 μm columns over a wide range of flow rate.

Van Deemter Curves : Correlation between linear velocity and column efficiency

Column 50 X 2.0 or 2.1 mmI.D.
Eluent acetonitrile/water (60/40)
Temperature 25°C
Detection butyl benzoate

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Low pressure and high throughput

The operating pressure of Meteoric Core is one half to one fifths of sub-2 μm Core-Shell type columns. High throughput analysis using Meteoric Core could be expected even with longer length columns since the usable maximum flow rate of it is higher than competitors’ sub-2 μm Core-Shell.

Column Pressure : Correlation between linear velocity and column backpressure

Column 50 X 2.0 or 2.1 mmI.D.
Eluent acetonitrile/water (60/40)
Temperature 25°C
Sample butyl benzoate

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Ultra fast analysis and excellent resolution

Meteoric Core C18 can shorten the analysis time by two thirds compared to the conventional fully porous C18 column with the same column dimension and under the same analysis condition. Moreover, it maintains the theoretical plate number at a two times faster flow rate. It allows us to decrease analysis time by one thirds while maintaining resolution, and at an operating pressure less than 5,000 psi.

1. Methyl p-hydroxybenzoate
2. Ethyl p-hydroxybenzoate
3. Isopropyl p-hydroxybenzoate
4. Propyl p-hydroxybenzoate
5. Isobutyl p-hydroxybenzoate
6. Butyl p-hydroxybenzoate
Column 150 X 3.0 mmI.D.
Eluent acetonitrile/water (50/50)
Temperature   30°C
Detection UV at 270 nm

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