HPLC preparative

K-Prep

Process chromatography

K-Prep

Accommodates preparative columns whose inner diameters range from 20-200mm. The purification of high-valued added substances is accomplished using K-Prep and chromatography packing material with particle sizes ranging from 5 to 20 um. The system is a fully automatic system with pressure limit of 100kg/cm2.

POINT

  • Easy operation.
  • Fully automated continuous operation via computer control.
  • Precise and speedy isolation by isocratic or gradient elution operation.
  • Economically efficient with recycle separation.
  • Compact.
  • Simple maintenance.
  • Easy expansion.
  • Comply with GLP/GMP validation.

USAGE

  • Separation for peptides,proteins etc.
  • Separation for intermediate of food products, pharmaceuticals and agrichemicals.
  • Separation for fermented products.


Fully automatic operation

Mobile phase, pump, automatic injector, wash valve, column switch valve, recycle valve, fraction collector all operate by computer control. K-Prep software records the real-time chromatogram and pressure. Outstanding user friendliness and reliability by programmable logic controller (PLC) allows remote control over each unit of the system.

Fully automatic operation by a computer

page top

Manual control with easy operation

By clicking an icon on the PC display, the corresponding apparatus is manually adjusted.
K-Prep is a flexible system and can be used in a variety of chromatography modes.

Manual control with easy operation

It has a high rate of recovery and selectivity. It can meet various kinds of needs of the preparative liquid chromatograph.

It has a high rate of recovery and selectivity. It can meet any needs of the preparative liquid chromatogram.

page top

Easy maintenance and expansion

Valves, pressure gauge, gradient mixers etc. are unitized to allow easy replacement in the unlikely event of a failure.
Pump can be easily pulled out by use of a slide rail for easy maintenance.

Interior of the apparatus is easily maintained and expanded.

page top

Up to 50mL(100mL) sample injection is possible

The automatic injector is equipped with 50mL(and/or 100mL) sample loop in conjunction with a high pressure 6-port valve and a syringe. The sample is drawn into the loop as many times as needed, using 25mL syringe (standard), so that the required quantity of the sample can be injected. When a large quantity of sample is needed, the injection should be carried out by means of a pump.

page top

Powerful high precision pump unit

Adoption of double plungers and a high precision servo-motor minimizes pressure pulsations and allows high precision delivery of the solvent down to 1/1000 of the maximum flow rate.

Powerful high precision pump unit

page top

Motor driven valve with low dead volume structure

The low dead volume structure permits quick solvent changeover and optimal gradient performance.
The thick orifice allow the mobile phase to moves very smoothly. YMC have developed a special structure of air driven value which is superior in operability and a device of unlimited drop system for fraction collector. The low dead volume with washing capability will perform fraction with less contamination.

page top

Compliance with GLP,GMP validation

  • Comply with system validation when it is delivered.
  • Comply with computer system validation when it is delivered.
  • Records of operation necessary for GLP and GMP will be created automatically.
  • The name of the file will not be overwritten after created mechanically.
  • Security management is established including passwords and identification codes entry.

Applied to GLP,GMP validation

page top



Products

Process chromatography

Process chromatography
YMC offers contract process chromatography purification services and produces Dynamic Axial Compression (DAC) systems and other types of systems and devices used for preparative chromatography.